[Mikendebbie]

My radio has 3 buttons on the upper right hand corner to choose which speakers are ON…I don’t recall if they are A B C or 1 2 3. I labeled mine…
LR (living room)
BR (bed room)
OUT ( out side speakers)

Each button is simple ON/OFF so you can have all 3 on at the same time or selectively. My TV plays thru the Bose sound bar which is controlled in the TV settings - not thru the radio buttons. I’m not sure I answered your question about “isolating” speakers - but that is the way mine work.