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George, If you can avoid the Chicago mess do so. If it were me I'd come down I-29 through Omaha and go to St. Joseph, MO then take Hwy 36 east out of St Joe to Hannibal and go South from there and across East to Goldsboro. We head to Alabama frequently and that is the way we take which avoids any large city traffic. St Louis is the only big city you would have to contend with and you can avoid it by taking the interstate that goes around it to the north of the city and comes out on the Illinois side of the Mississippi!
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